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email: pogo@orange.ichtj.waw.pl, pogo@tele2.pl |
September 2004 D.Sc. in chemistry, Institute of Nuclear Chemistry and Technology.
Dissertation: "Participation of oxidized sulfur center in intramolecular free radical
processes in the model organic compounds of biological importance" December
1996 Ph.D. in chemistry with "honors", Institute of Nuclear Chemistry and Technology.
Thesis: "Investigation of radical processes induced by hydroxyl radical in amino
acids and peptides containing thioether group"("Badanie
Procesów Rodnikowych w Aminokwasach i Peptydach Zawierających Grupę Tioeterową,
Indukowanych Rodnikami Wodorotlenkowymi")
September 1987 M.Sc. in organic chemistry and technology, Technical University of
Łódź, Department of Chemistry.Thesis: "Pulse radiolysis of alcohols-water mixed solution"
05/2004-06/2004
IAEA fellow in
the Department of Chemistry. University of Calgary. Research supervisor; Prof.
A. Rauk. Topic: computational chemistry.
10/1998 - 10/2001 
Postdoc in the Department
of Pharmaceutical Chemistry. University of Kansas.
Research supervisor; Assoc.
Prof. Ch. Schöneich, Topic: pharmaceutical chemistry, computational chemistry
July 1998
Guest researcher
in the Laboratorie de Chemie Théoretique, Universite P. et. M. Curie, Paris, France.
Research supervisor; Prof. J. Bergés, Topic: computational chemistry05/1997 - 09/1998
Analytical
specialist A.G.A. Analytical. (Dionex Co. (USA) representative in Poland). Topic:ion
chromatography, scientific information, new applications
Guest
researcher in the Riso National Laboratory, Denmark, Research supervisor;
Dr. J. Holcman, Topic: flash photolysis Since 11/1987
Senior scientist
(1997-), Research assistant (1990-), chemist (1987-) in the Department
of Radiation Chemistry and Technology. Institute of Nuclear Chemistry and Technology,
Warsaw. Research director: Prof. K. Bobrowski, Dr. J. Grodkowski, Topic: radiation
chemistry and dosimetry, free radicals reactions, electron transfer reactions, transient
and final products identification02/1994 - 04/1994, 04/1993 - 10/1993
Guest researcher
in the Hahn-Meitner-Institut Berlin. Germany (Association for International Cancer
Research fellowship), Research director; Prof. K.-D. Asmus, Topic: free radicals
reactiona in organic thioethers, final products identification.
04/1993-10/1993
IAEA fellow
in the Institute of Isotopes the Hungarian Academy of Sciences. Budapest. Hungary.
(International Atomic Energy Agency - fellowship), Research director; Prof. L. Wojnarovits.
Topic: free radicals reactions in organic thioethers, pulse radiolysis.07/1990-03/1993
Proof-reader
in the Abstract sp.z.o.o. (The Balsthein Institute (Germany) delegation in Poland.)
Topic: scientific information. organic chemistry.10/1986-06/1987
Technician at
the Technical University of Łódź, Institute of Applied Radiation Chemistry. Research director;
Prof. J. Kroh, Assoc. Prof. Z. Czerwik. Topic: pulse radiolysis, radiation chemistry
2004, 2002, 1999, 1996, 1994 Institute of Nuclear Chemistry and Technology Director's
Award
1996
Scientific Council of the Institute of Nuclear Chemistry and Technology Award1993
"Young Investigator Travel Award" of the Baxendale Fund for attendanceof Miller-Conference
in England,
Utlenianie
tioeterów przez kompleksy miedzio-organiczne. Procesy o potencjalnym znaczeniu dla
patogenezy niektórych chorób neurodegeneracyjnych (Oxidation of thioethers through
the organic copper complexes. Processes of potential importance for pathogenesis
of some neurodegenerative diseases) Grant KBN 3 T09A 066 26.
Modelowanie
molekularne białka
Wewnątrzcząsteczkowe
przemiany rodnikowe z udziałem utlenionego centrum siarkowego w modelowych zwi±zkach
tioeterowych o znaczeniu biologicznym. (Participation of oxidized sulfur center in
intramolecular free radical processes in the model organic compounds of biological
importance) D. Pogocki, Raporty IChTJ. Seria A nr 2, 5-87 (2004).
Mutation
of the Phe20 residue in Alzheimer’s amyloid b-peptide
might decrease its toxicity due to disruption of the Met35 - cupric site
electron-transfer pathway. D. Pogocki, Chem. Res. Toxicol., 17, 325-329 (2004).
Interaction
of silver atoms with ethylene in Ag-SAPO-11 molecular sieve. EPR and DFT study. M. Danilczuk,
D. Pogocki, A. Lund, J. Michalik. Phys.Chem.Chem.Phys., 6, 1165-1168
(2004).
Free
radicals reactions of methionine in peptides: mechanism relevant to b-amyloid
oxidation in Alzheimer's disease. Ch. Schöneich, D. Pogocki, G. L. Hug, K.
Bobrowski. J. Am. Chem. Soc., 125, 13700-13713 (2003).Neurotoksyczno¶ć
amyloidowego b-peptydu Alzheimera
rolaMet35 i miedzi kompleksowanej przez peptyd. (Neurotoxicity of Alzheimer
amyloid b-peptide, function of Met35 and copper
complexed by the peptide.)D. Pogocki, K.Serdiuk, Wiadomości Chemiczne, 57,
459-475 (2003).Computational
characterizationof sulfur-oxygen three-electron-bonded radicals in methionine and
methionine-containing peptides:Important intermediates in one-electron oxidation
processes. D. Pogocki, K.Serdiuk, Ch. Schöneich, J. Phys. Chem. A., 107, 7032-7042
(2003).Alzheimer's
b-amyloidpeptide as a source of neurotoxic free radicals:
The role of structural effects.D. Pogocki, Acta Neurobiol. Exp., 63, 131-145
(2003).Redox
properties of Met35 in neurotoxic b-amyloid peptide.
A molecularmodeling study. D. Pogocki, Ch. Schöneich, Chem. Res. Toxicol.,
15, 408-418 (2002).
Computational characterization of sulfur-oxygen bonded sulfuranyl radicals derived
from alkyl- and (carboxyalkyl) thiopropionic acids: evidence for s*-type
radicals.D. Pogocki, Ch. Schöneich, J. Org. Chem., 67, 1526-1535 (2002).Thiyl
radicals abstract hydrogen atoms from carbohydrates: Reactivity and selectivity.D.
Pogocki, Ch. Schöneich, Free Radical Biol. Med., 31, 98-107 (2001).Conformational
flexibility controls proton transfer between the methionine hydroxysulfuranyl radical
and the N-terminal amino group in Thr-(X)n-Met peptides.D. Pogocki,
E. Ghezzo-Schöneich, Ch. Schöneich J. Phys. Chem. B., 105, 1250-1259 (2001).Intramolecular
sulfur-oxygen bond formation in radical cations of N-acetylmethionineamide. Ch. Schöneich,
D. Pogocki, P. Wisniowski, G. L. Hug, K. Bobrowski, J.Am. Chem. Soc., 122,
10224-10225 (2000).Hydroxyl
radical induced oxidation of thiaproline derivatives. An ESR Study. D.Pogocki,
J. Sadlo, Nukleonika, 45, 101-108 (2000).Chemical
stability of nucleic acid derived drugs. D. Pogocki, Ch. Schöneich, J. Pharm.
Sci. 89, 443-456 (2000).
Oxidation of (carboxyl)thiopropionic acid derivatives by hydroxyl radicals. Mechanism
and kinetics of competitive inter- and intramolecular formation of s-
and s*-typesulfuranyl radicals. K. Bobrowski, D. Pogocki,
Ch. Schöneich, J.Phys. Chem.A., 102, 10512-10521 (1998).Wstęp
do chromatografii jonowej (Introduction to ion chromatography).D.Pogocki,
A.G.A. Analytical Monograph p. 1-54 (1998).
